RNA TARGETS IN BIOLOGY AND MEDICINE

     

    

1 INFECTIOUS DISEASE   
HIV: DRUGS THAT SUPPRESS THE TAR STEMLOOP FROM INTERACTING WITH A TAT TRANS-ACTIVATOR. 

ANTIBIOTICS: i.e: BACTERIAL RIBOSOME PEPTIDAL TRANSFERASE IS BLOCKED BY ERYTHROMYCIN



2 ARTHRITIS/CANCER  (Message Pharmaceuticals)

CYTOKINE mRNAs: DRUGS THAT SUPPRESS AUF-1 BINDING TO THE 3'UTRS OF IL-1- AND TNF-mRNAs

     Oxandrolone contributes to a strong increase in strength. This is due to the fact that the synthesis of creatin phosphate is raised in the muscle cell and does not accumulate fluid. Weightlifters and security forces that do not want to move to a higher category use this as drug gives them a chance to get stronger, not adding to their own weight. Good results are obtained simultaneous reception of Oxandrolone and 120 - 140mg Clenbuterol per day.  

      This is due to the fact that it contributes to a strong increase in strength., and significantly enhances the effect of many steroids on the body, especially combined with Deca-Durabolin, Dianabol and a variety of testosterone, as arises when taking Oxandrolone strength gains while Deca-Durabolin, Dianabol or testosterone that accumulate fluid and contribute to strong growth in tissue, the result is an additional muscle mass.  

     The combination of 200 mg Deca per week, 500 mg of testosterone enanthate per week and 25 mg Oxandrolone day causes most athletes a good gain in strength and muscle mass. Deca-Durabolin has a distinct anabolic effect and stimulates the synthesis of proteins, oxandrolone increases strength, and testosterone makes the athlete more aggressive during the workout and accelerates regeneration.

Oxandrolone does not have any side effects

    Oxandrolone in reasonable doses does not have any side effects. This is understandable, since drug originally designed for women and children. This is one of the few steroids which does not cause a delay premature physical development of children, as it does not promote closure epofizez  compounds, and the drug is primarily used in children to stimulate growth of the body and women - in osteoporosis. The drug causes (if any is) very weak virilization.  

  This quality makes it a favorite means of athletes as at a dose of 10-15 mg a day they rarely observed outward manifestations of masculinity. Oxandrolone love bodybuilding and powerlifting athletes.

Oxandrolone

    Oxandrolone appeared in the U.S. in 1964. Anavar called the company "Searle." Over two decades, was very popular until July 1, 1986 did not stop the production of Anavar. Today, the drug is still produced under different names.  

    Oxandrolone SPA company "SPA Milano" from Italy is one of the few in Europe anabolic steroid containing the substance (oxandrolone).

The dosage of testosterone

      Not all that rare, as among bodybuilders and powerlifters in the environment, are the dosages of testosterone enanthate 2000 mg per day. It was a day, not a week. As ordinary user to such doses do not go up, it can be limited to the same two grams of the drug, but in a week. A normal return on testosterone enanthate starts with 500 mg per week, although this is, nevertheless, the dosage for beginners in the "steroids."
     Injections of testosterone enanthate can be done once in 5-7 days, but I would recommend more frequent injections.

Side effects of testosterone

     Since testosterone is easily aromatized, its use in high doses can cause side effects such as water retention, acne, deposition of fat on the female type. But for most athletes, the problem begins with high doses of the drug - from grams per week and up, with both doses of testosterone are advised to take antiestrogens at least the same tamoxifen. With doses of 500-600 mg of testosterone enanthate per week, the person who uses testosterone, can not notice any "side effects"The conversion of testosterone to DHT means a risk of side effects such as hair loss and prostate enlargement. Again, this only applies to high dosages of the drug and is characteristic only for those people who have in the skin of the head and the prostate has been an increased level of the enzyme 5Reductase. 
    The use of testosterone, even at doses of more than two grams a week did not infringe either the liver or other organs. And the restoration of natural testosterone production after such a shock, "course" is very successful, without delay.

The use of testosterone

    When people talk about testosterone, primarily mean those in which the active substance is testosterone enanthate. This broadcast we will look at in the first place.
 
    The only purpose of testosterone enanthate - help in the set weight. And the task he handles a hundred percent. Increased tendency to flavor here for the benefit of the drug, since estradiol has provided substantial assistance in the collection of mass. In the case of high-dose testosterone enanthate muscle mass may be the result of the formation of new fibers (hyperplasia of the muscles). Testosterone enanthate has the influence and the power of the athlete, of course, in the direction of improvement. The uniqueness of testosterone is that it has an equally strong impact on both beginners and veterans in the "steroid front."